OC02.10: Fetal medication does not modify fetal brain development in a rabbit model

Fetal brain development in chimpanzees versus humans

chimpanzee, 34–35 weeks) [4], human neonates do have larger brains than chimpanzee neonates [2]. It has been suggested that the extraordinary brain enlargement in humans is due to unique features in the human pattern of brain development during both the prenatal and postnatal periods [1,2]. It has been argued that all primates conform to a 12% ratio of brain mass to body mass from the fetal per...

Diethylphthalate, Possible Interactions in Fetal Brain Development

Many natural and synthetic compounds, including a variety of the chemicals used as plasticizers or in the production of cosmetics and therapeutics, have steroid agonist or antagonist activities, altering hormone-regulated gene expression. The phthalate (diethylphthalate, extensively used as a plasticizer and in consumer products, are evaluated using the human renal epithelial cell line 293T/17....

Effects of lactation on fetal survival and development in rabbit does mated shortly after parturition.

Primiparous rabbit does were mated within 12 h after parturition (d 0). They were immediately weaned (Group W; n = 31) or allowed to suckle 10 young rabbits (Group L; n = 32). Blood samples were collected at d 0, 7, 17, and 28. Feed intake and live weight were measured weekly and pregnant does (Group W, n = 24; Group L = 25) were slaughtered at d 28. Feed intake was 78% higher in L than in W fe...

Control of fetal lung development in the rabbit.

Protective effect of baicalin on fetal lung development in a rabbit model of congenital diaphragmatic hernia

Bacalin has been reported to improve fetal lung growth by increasing fetal lung surfactant phospholipids. Therefore, the present study evaluated the effect of transplacental treatment of baicalin during lung development in rabbits with congenital diaphragmatic hernia (DH) rabbit. DH was induced in fetal rabbit on gestational day 23 and baicalin injections were administered daily until term peri...